Antiretroviral release from poly(DL-lactide-co-glycolide) nanoparticles in mice
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چکیده
منابع مشابه
Antiretroviral release from poly(DL-lactide-co-glycolide) nanoparticles in mice.
OBJECTIVES Free ritonavir, lopinavir and efavirenz injected intraperitoneally were compared with antiretroviral (AR) nanoparticles (NPs). METHODS This is a prospective study in BALB/c mice comparing the pharmacokinetics of free drugs with AR NPs. All animals received free drugs or AR NPs (20 mg/kg) in PBS. In vitro replication assays were used for determination of the anti-HIV efficacy of NP ...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2010
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkq318